On a New Organic Base in the Coca Leaves

On a New Organic Base in the Coca Leaves is an 1860 dissertation written by Dr. Albert Niemann. The piece describes, in detail, how Niemann isolated cocaine, a crystalline alkaloid. It also earned Niemann his Ph.D. and is now in the British Library. He wrote of the alkaloid's "colourless transparent prisms" and said that, "Its solutions have an alkaline reaction, a bitter taste, promote the flow of saliva and leave a peculiar numbness, followed by a a sense of cold when applied to the tongue." Niemann named the alkaloid "cocaine" — as with other alkaloids its name carried the "-ine" suffix.