Haldane's dilemma
(Redirected from Haldanes dilemma)
Haldane's dilemma refers to a paradox introduced by J. B. S. Haldane concerning the efficacy of natural selection. Haldane was concerned that it would take 300 generations to fix a single gene from initial mutation to ubiquity in a population. While one can debate this figure, it is not the main source of the dilemma. This comes from the invalid assumptions that only one gene can be fixed at a time and that no other changes can accumulate until the ongoing one is fixed. That is why multiplying the number of generations per fixation by the number of total DNA differences makes no sense.
External links
Categories: Population genetics