Gattilusio

The Gattilusio family was the ruling dynasty of the island of Lesbos from 1355 to 1462, when the last prince was strangled on the orders of Sultan Mehmed II. A junior branch of the family ruled Ainos until 1488. The family's origin was Genoese, the founder being a mercenary who assisted John V Palaeologus regain his throne and, as means of payment, received a princedom and the hand of the Emperor's sister, Maria Palaiologina.

Princes of Lesbos

• Francesco I of Lesbos (1355–1384)
• Francesco II of Lesbos (1384–1404)
• Jacopo of Lesbos (1404–1428)
• Dorino of Lesbos (1428–1455)
• Domenico of Lesbos (1455–1458)
• Niccolo of Lesbos (1458–1462)

Princes of Ainos

• Niccolo of Ainos (1355–1409), younger brother of Francesco I.
• Palamede of Ainos (1409–1455), younger brother of Jacopo and Dorino.
• Dorino of Ainos (1455–1488), son of Palamede, ceded his rights to his brother-in-law.