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Myelofibrosis

Myelofibrosis is the gradual replacement of the bone marrow by connective tissue. Its main feature is "extramedullary hematopoeisis", i.e. the blood-forming cells migrate to other sites in the body, e.g. the liver or spleen. Typically affects patients > 50 years. Patients will typically have hepatosplenomegaly, and the blood smear will show "teardrop cells".


Health science – Medicine – Hematology
Hematological malignancy and White blood cells
Leukemia (ALL, AML, CLL, CML) – Lymphoma (Hodgkin's disease, NHL) – Multiple myeloma – MDS – Myelofibrosis – Myeloproliferative disease (Thrombocytosis, Polycythemia) – Neutropenia
Red blood cells
Anemia – Hemochromatosis – Sickle-cell anemia – Thalassemia – G6PD – other hemoglobinopathies
Coagulation and Platelets
Thrombosis – Deep venous thrombosis – Pulmonary embolism – Hemophilia – ITP – TTP







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